Our laboratory develops and applies novel methods of single-molecule manipulation and detection, such as optical tweezers, single-molecule fluorescence microscopy, ‘fleezers’ (fluorescence-force hybrid instrument), and nanopore. Additionally, we also strive to complement dynamic studies of biological systems with structural investigations using cryo-EM and cryo-ET.

These techniques are used to understand:
• Transcription through Nucleosomes
• Translation
• Protein Folding
• Recombination
• Protein Degradation

We are affiliated with the departments of Molecular and Cell Biology, Physics, and Chemistry as well as the Physical Biosciences Division at Lawrence Berkeley National Laboratory.

Feel free to attend our group meetings to learn more about our work.

To contact Prof. Carlos Bustamante: Office: 608A Stanley Hall E-mail: carlosb at berkeley dot edu Phone: (510) 643-9706 Fax: (510) 643-4500

Administrative contacts: Natalie Thung 608 Stanley Hall E-mail: nthung at berkeley dot edu Phone: (510) 642-3238

Main Lab: Lab Phone: (510) 666-2759 University of California QB3 Institute 642 Stanley Hall #3220 Berkeley, CA 94720-3220