The Bustamante Lab

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Our laboratory develops and applies novel methods of single-molecule manipulation and detection, such as optical tweezers, single-molecule fluorescence microscopy, ‘fleezers’ (fluorescence-force hybrid instrument), and nanopore.

These techniques are used to understand:
• DNA packaging into bacteriophage Φ29 capsids
• Transcription
• Translation and Protein Folding
• Protein degradation by ClpXP
• Catalysis-enhanced enzyme diffusion

We are affiliated with the departments of Molecular and Cell Biology, Physics, and Chemistry as well as the Physical Biosciences Division at Lawrence Berkeley National Laboratory.

Feel free to attend our group meetings to learn more about our work.

To contact Prof. Carlos Bustamante:
Office: 608A Stanley Hall
E-mail: carlosb at berkeley dot edu
Phone: (510) 643-9706
Fax: (510) 643-4500
Administrative contacts:
Natalie Thung
608 Stanley Hall
E-mail: nthung at berkeley dot edu
Phone: (510) 642-3238
Main Lab:
Lab Phone: (510) 666-2759
University of California
QB3 Institute
642 Stanley Hall #3220
Berkeley, CA 94720-3220

Single Molecule Biophysics at UC Berkeley